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Reaction Details
Reaction:	1.0 + 1.0 + 1.0 + 1.0 ↔ 1.0 + 1.0 + 1.0
	1.0alpha-Ketoisovaleric acid + 1.0Acetyl-CoA + 1.0Water + 1.0a-Ketoisovaleric acid ↔ 1.02-Isopropylmalic acid + 1.0Coenzyme A + 1.0Hydrogen ion
Enzymes:	2-isopropylmalate synthase
External Links:	Resource Link Kegg Reaction ID: R01213
References:	Orth, J. D., Conrad, T. M., Na, J., Lerman, J. A., Nam, H., Feist, A. M., Palsson, B. O. (2011). "A comprehensive genome-scale reconstruction of Escherichia coli metabolism--2011." Mol Syst Biol 7:535. Pubmed: 21988831