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Record Information
Version	2.0
Creation Date	2015-09-08 17:50:06 -0600
Update Date	2015-09-14 16:46:35 -0600
Secondary Accession Numbers	ECMDB24214
Identification
Name:	D-ribofuranose 5-phosphate
Description	D-ribofuranose 5-phosphate is an intermediate in several pathways in E. coli., adenosine nucleotides degradation III, NAD salvage pathway I and D-ribofuranose 5-phosphate pathway. In adenosine nucleotides degradation III pathway, it is a product for enzyme AMP nucleosidase which catalyzes the reaction AMP + H2O -> D-ribofuranose 5-phosphate + adenine. It is also a product for enzyme NMN nucleosidase that catalyzes the reaction beta-nicotinamide D-ribonucleotide + H2O -> D-ribofuranose 5-phosphate + nicotinamide + H+ in pathway NAD salvage pathway I. It is a substrate for enzyme pseudouridine 5'-phosphate glycosidase that catalyzes the reaction D-ribofuranose 5-phosphate + uracil -> pseudouridine 5'-phosphate + H2O in pseudouridine degradation pathway (BioCyc compound: CPD-15317).
Structure	MOLSDF3D-SDFPDBSMILESInChI View 3D Structure × Structure for #<Compound:0x52f64c4c> Close
Synonyms:	D-Ribofuranose 5-phosphoric acid
Chemical Formula:	C5H9O8P
Weight:	Average: 228.094 Monoisotopic: 228.004601408
InChI Key:	KTVPXOYAKDPRHY-UHFFFAOYSA-L
InChI:	InChI=1S/C5H11O8P/c6-3-2(1-12-14(9,10)11)13-5(8)4(3)7/h2-8H,1H2,(H2,9,10,11)/p-2
CAS number:	Not Available
IUPAC Name:	(3,4,5-trihydroxyoxolan-2-yl)methyl phosphate
Traditional IUPAC Name:	(3,4,5-trihydroxyoxolan-2-yl)methyl phosphate
SMILES:	OC1OC(COP([O-])([O-])=O)C(O)C1O
Chemical Taxonomy
Description	belongs to the class of organic compounds known as pentose phosphates. These are carbohydrate derivatives containing a pentose substituted by one or more phosphate groups.
Kingdom	Organic compounds
Super Class	Organic oxygen compounds
Class	Organooxygen compounds
Sub Class	Carbohydrates and carbohydrate conjugates
Direct Parent	Pentose phosphates
Alternative Parents	Monosaccharide phosphates Alkyl phosphates Oxolanes Secondary alcohols Hemiacetals 1,2-diols Oxacyclic compounds Organic oxides Hydrocarbon derivatives Organic anions
Substituents	Pentose phosphate Pentose-5-phosphate Monosaccharide phosphate Organic phosphoric acid derivative Phosphoric acid ester Alkyl phosphate Oxolane Secondary alcohol 1,2-diol Hemiacetal Polyol Oxacycle Organoheterocyclic compound Alcohol Hydrocarbon derivative Organic oxide Organic anion Aliphatic heteromonocyclic compound
Molecular Framework	Aliphatic heteromonocyclic compounds
External Descriptors	a pentose-5-phosphate (RIBOSE-5P )
Physical Properties
State:	Not Available
Charge:	-2
Melting point:	Not Available
Experimental Properties:	Property Value Source
Predicted Properties	Property Value Source Water Solubility 91.5 g/L ALOGPS logP -2 ALOGPS logP -2.4 ChemAxon logS -0.46 ALOGPS pKa (Strongest Acidic) 1.22 ChemAxon pKa (Strongest Basic) -3.7 ChemAxon Physiological Charge -2 ChemAxon Hydrogen Acceptor Count 7 ChemAxon Hydrogen Donor Count 3 ChemAxon Polar Surface Area 142.34 Ų ChemAxon Rotatable Bond Count 3 ChemAxon Refractivity 38.59 m³·mol⁻¹ ChemAxon Polarizability 17.71 ų ChemAxon Number of Rings 1 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule Yes ChemAxon
Biological Properties
Cellular Locations:	Cytoplasm
Reactions:	Pseudouridine 5'-phosphate + Water > Uracil + D-ribofuranose 5-phosphate + D-ribofuranose 5-phosphate
SMPDB Pathways:	NAD salvage PW000830 Purine degradation PW001887
KEGG Pathways:	Not Available
EcoCyc Pathways:	Not Available
Concentrations
	Not Available
Spectra
Spectra:	Spectrum Type Description Splash Key Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 10V, Positive splash10-004i-0590000000-2ad1e1777afc19197498 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 20V, Positive splash10-00lr-1940000000-dd45fecb62ac31c802b6 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 40V, Positive splash10-014i-9500000000-52100310a055a110dd60 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 10V, Negative splash10-004i-1090000000-c6d9c7e1519e62fed756 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 20V, Negative splash10-004i-2390000000-1f5559e015b7cb222e70 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 40V, Negative splash10-053v-9200000000-ec504f5f38fde4e1c9c2 View in MoNA 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer
References
References:	Not Available
Synthesis Reference:	Not Available
Material Safety Data Sheet (MSDS)	Not Available
Links
External Links:	Resource Link CHEBI ID Not Available HMDB ID Not Available Pubchem Compound ID 4357561 Kegg ID Not Available ChemSpider ID Not Available Wikipedia ID Not Available BioCyc ID Not Available