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Record Information
Version	2.0
Creation Date	2015-09-08 17:49:59 -0600
Update Date	2015-09-14 16:46:30 -0600
Secondary Accession Numbers	ECMDB24191
Identification
Name:	N2-succinylglutamate
Description	N2-succinylglutamate is an intermediate in L-arginine degradation II pathway in E.coli. It is a product for the enzyme succinylglutamate desuccinylase which catalyzes the reaction N2-succinyl-L-glutamate 5-semialdehyde + NAD+ + H2O -> N2-succinylglutamate + NADH + 2 H+. It is also the substrate for the enzyme succinylglutamate semialdehyde dehydrogenase which catalyzes the reaction N2-succinylglutamate + H2O -> succinate + L-glutamate (BioCyc: N2-SUCCINYLGLUTAMATE).
Structure	MOLSDFPDBSMILESInChI × Structure for #<Compound:0xb081ad70> Close
Synonyms:	N2-Succinylglutamic acid
Chemical Formula:	C9H10NO7
Weight:	Average: 244.181 Monoisotopic: 244.047372406
InChI Key:	JCNBNOQGFSXOML-YFKPBYRVSA-K
InChI:	InChI=1S/C9H13NO7/c11-6(2-4-8(14)15)10-5(9(16)17)1-3-7(12)13/h5H,1-4H2,(H,10,11)(H,12,13)(H,14,15)(H,16,17)/p-3/t5-/m0/s1
CAS number:	Not Available
IUPAC Name:	(2S)-2-(3-carboxylatopropanamido)pentanedioate
Traditional IUPAC Name:	N-succinyl-L-glutamate
SMILES:	[O-]C(=O)CC[C@H](NC(=O)CCC([O-])=O)C([O-])=O
Chemical Taxonomy
Description	belongs to the class of organic compounds known as glutamic acid and derivatives. Glutamic acid and derivatives are compounds containing glutamic acid or a derivative thereof resulting from reaction of glutamic acid at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
Kingdom	Organic compounds
Super Class	Organic acids and derivatives
Class	Carboxylic acids and derivatives
Sub Class	Amino acids, peptides, and analogues
Direct Parent	Glutamic acid and derivatives
Alternative Parents	N-acyl-L-alpha-amino acids Tricarboxylic acids and derivatives N-acyl amines Secondary carboxylic acid amides Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Organic anions
Substituents	Glutamic acid or derivatives N-acyl-alpha-amino acid N-acyl-alpha amino acid or derivatives N-acyl-l-alpha-amino acid Tricarboxylic acid or derivatives Fatty amide N-acyl-amine Fatty acyl Carboxamide group Secondary carboxylic acid amide Carboxylic acid Carbonyl group Organooxygen compound Organonitrogen compound Organic oxide Organopnictogen compound Organic oxygen compound Organic nitrogen compound Hydrocarbon derivative Organic anion Aliphatic acyclic compound
Molecular Framework	Aliphatic acyclic compounds
External Descriptors	tricarboxylic acid trianion (CHEBI:58763 )
Physical Properties
State:	Not Available
Charge:	-3
Melting point:	Not Available
Experimental Properties:	Property Value Source
Predicted Properties	Property Value Source Water Solubility 38.2 g/L ALOGPS logP -0.5 ALOGPS logP -1.3 ChemAxon logS -0.89 ALOGPS pKa (Strongest Acidic) 3.15 ChemAxon pKa (Strongest Basic) -2 ChemAxon Physiological Charge -3 ChemAxon Hydrogen Acceptor Count 7 ChemAxon Hydrogen Donor Count 1 ChemAxon Polar Surface Area 149.49 Ų ChemAxon Rotatable Bond Count 8 ChemAxon Refractivity 84.14 m³·mol⁻¹ ChemAxon Polarizability 21.06 ų ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule Yes ChemAxon MDDR-like Rule Yes ChemAxon
Biological Properties
Cellular Locations:	Cytoplasm
Reactions:	N2-Succinyl-L-glutamic acid 5-semialdehyde + Water + NAD >2 Hydrogen ion + NADH + N2-succinylglutamate + N2-succinylglutamate N2-succinylglutamate + Water + N2-succinylglutamate > L-Glutamic acid + Succinic acid + L-Glutamate
SMPDB Pathways:	arginine metabolism PW000790
KEGG Pathways:	Not Available
EcoCyc Pathways:	Not Available
Concentrations
	Not Available
Spectra
Spectra:	Spectrum Type Description Splash Key Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 10V, Negative splash10-0006-0090000000-f310facb2c5c7d473f9f View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 20V, Negative splash10-0006-0090000000-4e3d1f4027d83744ee1b View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 40V, Negative splash10-0a4i-9840000000-86bd929b2686738ed752 View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 10V, Positive splash10-0002-0090000000-626d5a6e0bb98ff7a5dd View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 20V, Positive splash10-000i-0290000000-cf9d16294246b066e0ca View in MoNA Predicted LC-MS/MS Predicted LC-MS/MS Spectrum - 40V, Positive splash10-00fr-9520000000-c78ca44a0f612788b215 View in MoNA 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer 1D NMR 13C NMR Spectrum Not Available View in JSpectraViewer 1D NMR 1H NMR Spectrum Not Available View in JSpectraViewer
References
References:	Not Available
Synthesis Reference:	Not Available
Material Safety Data Sheet (MSDS)	Not Available
Links
External Links:	Resource Link CHEBI ID 58763 HMDB ID Not Available Pubchem Compound ID 25244383 Kegg ID Not Available ChemSpider ID Not Available Wikipedia ID Not Available BioCyc ID Not Available

Enzymes