| Record Information |
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| Version | 2.0 |
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| Creation Date | 2012-10-10 12:22:14 -0600 |
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| Update Date | 2015-06-03 17:26:10 -0600 |
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| Secondary Accession Numbers | |
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| Identification |
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| Name: | 7-Aminomethyl-7-deazaguanosine |
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| Description | 7-Aminomethyl-7-deazaguanosine is an intermediate in tRNA charging and tRNA queosine synthesis. It is a substrate for S-adenosylmethionine:tRNA ribosyltransferase-isomerase which catalyzes the reaction: S-adenosylmethionine + 7-aminomethyl-7-deazaguanosine = methionine + adenine + epoxyqueuosine |
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| Structure | |
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| Synonyms: | - 2-amino-5-(aminomethyl)-7-(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl-1H-pyrrolo2,3-dpyrimidin-4-one
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| Chemical Formula: | C12H17N5O5 |
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| Weight: | Average: 311.2939
Monoisotopic: 311.122968679 |
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| InChI Key: | SOEYIPCQNRSIAV-IOSLPCCCSA-N |
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| InChI: | InChI=1S/C12H17N5O5/c13-1-4-2-17(9-6(4)10(21)16-12(14)15-9)11-8(20)7(19)5(3-18)22-11/h2,5,7-8,11,18-20H,1,3,13H2,(H3,14,15,16,21)/t5-,7-,8-,11-/m1/s1 |
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| CAS number: | Not Available |
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| IUPAC Name: | (2R,3R,4S,5R)-2-[5-(aminomethyl)-4-hydroxy-2-imino-1H,2H,7H-pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
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| Traditional IUPAC Name: | (2R,3R,4S,5R)-2-[5-(aminomethyl)-4-hydroxy-2-imino-1H-pyrrolo[2,3-d]pyrimidin-7-yl]-5-(hydroxymethyl)oxolane-3,4-diol |
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| SMILES: | [H][C@]1(CO)O[C@@]([H])(N2C=C(CN)C3=C2NC(=N)N=C3O)[C@]([H])(O)[C@]1([H])O |
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| Chemical Taxonomy |
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| Description | belongs to the class of organic compounds known as pyrrolopyrimidine nucleosides and nucleotides. These are nucleoside derivatives containing a ribose derivative which is n-glycosylated to a pyrrolopyrimidine. Also called deazapurine nucleosides, they are analogs of purine nucleosides with the N atom of the purine being replaced by a C atom at position 7. |
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| Kingdom | Organic compounds |
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| Super Class | Nucleosides, nucleotides, and analogues |
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| Class | Pyrrolopyrimidine nucleosides and nucleotides |
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| Sub Class | Not Available |
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| Direct Parent | Pyrrolopyrimidine nucleosides and nucleotides |
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| Alternative Parents | |
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| Substituents | - Pyrrolopyrimidine ribonucleoside
- N-glycosyl compound
- Glycosyl compound
- Pentose monosaccharide
- Pyrrolo[2,3-d]pyrimidine
- Pyrrolopyrimidine
- Aralkylamine
- Pyrimidone
- Aminopyrimidine
- Substituted pyrrole
- Pyrimidine
- Monosaccharide
- Heteroaromatic compound
- Vinylogous amide
- Tetrahydrofuran
- Pyrrole
- Secondary alcohol
- Oxacycle
- Azacycle
- Organoheterocyclic compound
- Organic nitrogen compound
- Organic oxygen compound
- Organopnictogen compound
- Organic oxide
- Hydrocarbon derivative
- Primary amine
- Primary alcohol
- Organooxygen compound
- Organonitrogen compound
- Primary aliphatic amine
- Amine
- Alcohol
- Aromatic heteropolycyclic compound
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| Molecular Framework | Aromatic heteropolycyclic compounds |
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| External Descriptors | Not Available |
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| Physical Properties |
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| State: | Not Available |
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| Charge: | 1 |
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| Melting point: | Not Available |
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| Experimental Properties: | |
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| Predicted Properties | |
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| Biological Properties |
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| Cellular Locations: | Cytoplasm |
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| Reactions: | |
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| SMPDB Pathways: | |
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| KEGG Pathways: | Not Available |
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| EcoCyc Pathways: | Not Available |
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| Concentrations |
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| Not Available |
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| Spectra |
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| Spectra: | |
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| References |
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| References: | Not Available |
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| Synthesis Reference: | Not Available |
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| Material Safety Data Sheet (MSDS) | Not Available |
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| Links |
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| External Links: | | Resource | Link |
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| CHEBI ID | Not Available | | HMDB ID | Not Available | | Pubchem Compound ID | 191792 | | Kegg ID | Not Available | | ChemSpider ID | Not Available | | Wikipedia ID | Not Available | | BioCyc ID | Not Available |
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