General function:

Carbohydrate transport and metabolism

Specific function:

Catalyzes the reversible isomerization between hydroxypyruvate and 2-hydroxy-3-oxopropanoate (also termed tartronate semialdehyde)

Gene Name:

hyi

Uniprot ID:

P30147

Molecular weight:

29377

Reactions

General function:

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Specific function:

Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Can also reduce 2,5-diketo-D-gluconate (25DKG) to 5-keto-D- gluconate (5KDG), 2-keto-D-gluconate (2KDG) to D-gluconate, and 2- keto-L-gulonate (2KLG) to L-idonate (IA), but it is not its physiological function. Inactive towards 2-oxoglutarate, oxaloacetate, pyruvate, 5-keto-D-gluconate, D-fructose and L- sorbose. Activity with NAD is very low

Gene Name:

ghrB

Uniprot ID:

P37666

Molecular weight:

35395

Reactions

General function:

Involved in hydrolase activity

Specific function:

Probably mediates the hydrolysis of some nucleoside diphosphate derivatives

Gene Name:

nudL

Uniprot ID:

P43337

Molecular weight:

21435

General function:

Involved in oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

Specific function:

Catalyzes the NADPH-dependent reduction of glyoxylate and hydroxypyruvate into glycolate and glycerate, respectively. Inactive towards 2-oxo-D-gluconate, 2-oxoglutarate, oxaloacetate and pyruvate. Only D- and L-glycerate are involved in the oxidative activity with NADP. Activity with NAD is very low

Gene Name:

ghrA

Uniprot ID:

P75913

Molecular weight:

35343

Reactions